Haemopoietic colony stimulating factors for preterm neonates
نویسندگان
چکیده
منابع مشابه
Haemopoietic colony stimulating factors for preterm neonates.
Bacterial and fungal sepsis is a major cause of morbidity and mortality in neonates. Infection rates are high in infants treated in intensive care units, with the highest rates, of around 30%, occurring in extremely immature preterm neonates. A survey of neonatal infection at Yale University, ongoing since 1928, has documented a decline in neonatal septic deaths commensurate with the establishm...
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Characteristics of neonatal neutrophils Polymorphonuclear neutrophils (PMN) are key components of the innate immune system, provide first line immune defence mechanisms against pathogenic challenge, and are both quantitatively and qualitatively deficient in neonates. Neutrophil deficiencies contribute significantly to the increased susceptibility of neonates to serious and overwhelming bacteria...
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متن کاملProduction of granulocyte colony-stimulating factor in vitro by monocytes from preterm and term neonates.
We postulated that defective generation of granulocyte colony-stimulating factor (G-CSF) by cells of newborn infants might underlie their deficiencies in upregulating neutrophil production and function during bacterial infection. To test this, we isolated monocytes from the blood of preterm neonates, term neonates, and adults and, after stimulation with various concentrations of interleukin-1 a...
متن کاملPrevalence of Preterm Neonates and Risk Factors
Introduction Preterm birth is still a major health problem throughout the world. Preterm birth results in 75% of neonatal mortality. We sought to identify risk factors which cause preterm birth. Materials and Methods This cross-sectional study assessed all preterm neonates born in Asali Hospital in Khorram Abad (either by NVD or C/S) during the first 6 months of 2007. Sampling method was censu...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood - Fetal and Neonatal Edition
سال: 1997
ISSN: 1359-2998,1468-2052
DOI: 10.1136/fn.76.2.f128